{"id":2018,"date":"2019-11-13T17:26:25","date_gmt":"2019-11-13T17:26:25","guid":{"rendered":"https:\/\/www.novatex-medical.com\/vitalised-study-presentation\/"},"modified":"2026-04-10T07:49:02","modified_gmt":"2026-04-10T07:49:02","slug":"vitalised-study-presentation","status":"publish","type":"post","link":"https:\/\/www.novatex-medical.com\/en\/vitalised-study-presentation\/","title":{"rendered":"VITALISED Study Overview"},"content":{"rendered":"\t\t
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VITALISED Study Overview<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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VITALISED \/ <\/strong>Evaluation of an innovative proprioceptive therapeutic approach in the treatment of hypermobile Ehlers-Danlos syndrome<\/em><\/p>

Project presentation<\/strong><\/em><\/p>

This study aims to better characterize hypermobile Ehlers-Danlos Syndrome (hEDS) and to evaluate the effectiveness of a non-pharmacological therapeutic strategy. This approach combines proprioceptive support through the use of compressive garments (NOVATEX MEDICAL) and sensorimotor reprogramming (SMR) on a motorized platform (HUBER 360\u00ae Evolution, LPG MEDICAL) to treat the sensorimotor impairment associated with hEDS.<\/em><\/p>

The study involves 40 hEDS patients and 40 control subjects. Patients will be monitored over a year, divided into three 4-month (M) periods: <\/em> : <\/em><\/p>

  • M0-M4 <\/strong>\u2013 Standardization of medical care.<\/em><\/li>
  • M4-M8<\/strong> \u2013 Sensorimotor reprogramming (12 sessions) combined with wearing compressive garments (experimental arm) or low-compression garments (control arm) for 6 hours a day.<\/em><\/li>
  • M8-M12<\/strong> \u2013 Discontinuation of the studied therapeutic strategy and evaluation of the lasting effects (at 4 months).<\/em><\/li><\/ul>


    Patients will be evaluated at each stage of the study (i.e., M0, M4, M8, and M12) using neuropsychological and perceptual tests, behavioral measurements (i.e., posture, locomotion) in virtual reality (i.e., sensory conflict and divided attention situation<\/em>s \u2013 kinematic, kinetic, and electromyographic analysis), as well as home questionnaires regarding symptoms (e.g., fatigue, anxiety, depression, pain, resilience, alexithymia) and quality of life (e.g., functional autonomy, mobility, sleep-wake rhythms).<\/em><\/p>

    Promoter and partners<\/strong><\/em><\/p>

    Caen University Hospital<\/strong> (Promoter), COMETE <\/strong>UMR-S 1075 INSERM-UNICAEN (Principal Investigator : Leslie DECKER, Coordinating Physician : Herv\u00e9 NORMAND), CIREVE <\/strong>\u2013 Centre Interdisciplinaire de R\u00e9alit\u00e9 Virtuelle (experimental site), NOVATEX MEDICAL<\/strong> (industrial partner).<\/em><\/p>

    Healthcare networks<\/strong><\/em><\/p>

    Caen University Hospital (Pain Evaluation and Treatment Center, Functional Explorations, Physical and Rehabilitation Medicine, Ophthalmology), Caen Rare Diseases Competence Center, National EDS Reference Center, Regional Health Training Institute (IFRS), SED\u2019in France association.<\/em><\/p>

    Doctoral theses<\/strong><\/em><\/p>

    Emma G. DUPUY<\/strong> (2015-2019, Supervised by: Leslie DECKER) and Valentin LANA<\/strong> (CIFRE COMETE\/DevAH\/NOVATEX MEDICAL, 2018-2021, Supervised by: Leslie DECKER & Julien FR\u00c8RE).<\/em><\/p>

    This project is co-financed by the European Union and the Normandy Region under the ERDF\/ESF 2014-2020 operational program.<\/em><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    VITALISED Study Overview VITALISED \/ Evaluation of an innovative proprioceptive therapeutic approach in the treatment of hypermobile Ehlers-Danlos syndrome Project presentation This study aims to better characterize hypermobile Ehlers-Danlos Syndrome (hEDS) and to evaluate the effectiveness of a non-pharmacological therapeutic strategy. This approach combines proprioceptive support through the use of compressive garments (NOVATEX MEDICAL) and […]<\/p>\n","protected":false},"author":1,"featured_media":1401,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"_seopress_robots_primary_cat":"none","_seopress_titles_title":"Vitalised study Ehlers-Danlos syndrome %%sep%% %%sitetitle%%","_seopress_titles_desc":"Evaluation of an innovative proprioceptive therapy for the treatment of hypermobile Ehlers-Danlos syndrome.","_seopress_robots_index":"","footnotes":""},"categories":[38],"tags":[],"class_list":{"0":"post-2018","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-news"},"_links":{"self":[{"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/posts\/2018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/comments?post=2018"}],"version-history":[{"count":7,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/posts\/2018\/revisions"}],"predecessor-version":[{"id":7773,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/posts\/2018\/revisions\/7773"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/media\/1401"}],"wp:attachment":[{"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/media?parent=2018"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/categories?post=2018"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.novatex-medical.com\/en\/wp-json\/wp\/v2\/tags?post=2018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}